Ube2i CLIA Kit for Mouse(Mus musculus) | EIAab.comUbe2i CLIA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Ube2i(Gene name) > Mouse

Ube2i (Gene name),

SUMO-conjugating enzyme UBC9 (Protein name ), UBC9_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Ube2i(Ubc9;Ubce2i;Ubce9);

Protein name:

SUMO-conjugating enzyme UBC9;

Alternative:

Ubiquitin carrier protein 9(mUBC9);SUMO-protein ligase;Ubiquitin-conjugating enzyme E2 I;Ubiquitin carrier protein I;Ubiquitin-protein ligase I;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Forms a tight complex with RANGAP1 and RANBP2. Interacts with SIAH1 and PARP. Interacts with various transcription factors such as TFAP2A, TFAP2B, TFAP2C, AR, ETS1 and SOX4. Interacts with RASD2. Interacts with RWDD3; the interaction enhances the sumoylation of a number of proteins such as HIF1A and I-kappa-B. Interacts with FOXL2. Forms a complex with SENP6 and UBE2I in response to UV irradiation. Interacts with DNM1L (via its GTPase and B domains); the interaction promotes sumoylation of DNM1L, mainly in the B domain (By similarity). Interacts with HIPK1, HIPK2, PPM1J and TCF3. Interacts with Moloney murine leukemia virus CA and adenovirus type 5 and type 12 E1A. Interacts with NR2C1; the interaction promotes its sumoylation. Interacts with NFATC2IP; this inhibits formation of poly-SUMO chains.

Function:

Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Essential for nuclear architecture, chromosome segregation and embryonic viability. Necessary for sumoylation of FOXL2 and KAT5.

Subcellular Location:

Nucleus Cytoplasm Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body.

Protein Attributes:

Sequence length:

158

Sequence:

50:

100:

150:

158:

QAKKFAPS

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

mmu:100044900

UniGene:

Mm.240044

String:

P63280

Pfam:

PF00179

SMR:

P63280

Uniprot:

P63280

FOR

ELISA Kit for Mouse SUMO-conjugating enzyme UBC9

MSDS:

Please sign in first.

ELISA Kit for Mouse SUMO-conjugating enzyme UBC9

Cat.:

E11134h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse SUMO-conjugating enzyme UBC9

Cat.:

E11134m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse SUMO-conjugating enzyme UBC9

Cat.:

E11134r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse SUMO-conjugating enzyme UBC9

Cat.:

U11134h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse SUMO-conjugating enzyme UBC9

MSDS:

Please sign in first.

CLIA Kit for Mouse SUMO-conjugating enzyme UBC9

Cat.:

U11134m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse SUMO-conjugating enzyme UBC9

Cat.:

U11134r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse SUMO-conjugating enzyme UBC9

Cat.:

P11134Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse SUMO-conjugating enzyme UBC9

Monoclonal Antibody for Mouse SUMO-conjugating enzyme UBC9

Protein for Mouse SUMO-conjugating enzyme UBC9

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha."
Scott L.M. , Mueller L. , Collins S.J.
Blood88:2517-2530(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: MDF1.
tissue: Promyelocytic leukemia.
2.

"mUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect."
Hateboer G. , Hijmans E.M. , Nooij J.B.D. , Schlenker S. , Jentsch S. , Bernards R.
J. Biol. Chem.271:25906-25911(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH ADENOVIRUS TYPE 5 AND TYPE 12 E1A
3.

"Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes."
Kovalenko O.V. , Plug A.W. , Haaf T. , Gonda D.K. , Ashley T. , Ward D.C. , Radding C.M. , Golub E.I.
Proc. Natl. Acad. Sci. U.S.A.93:2958-2963(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
4.

"The mUBC9 murine ubiquitin conjugating enzyme interacts with the E2A transcription factors."
Loveys D.A. , Streiff M.B. , Schaefer T.S. , Kato G.J.
Gene201:169-177(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INTERACTION WITH TCF3
strain: BALB/c.
tissue: Fibroblast.
5.

"Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IkappaBalpha."
Tashiro K. , Pando M.P. , Kanegae Y. , Wamsley P.M. , Inoue S. , Verma I.M.
Proc. Natl. Acad. Sci. U.S.A.94:7862-7867(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
tissue: B-cell lymphoma.
6.

Weber B.
Submitted (1997-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: PJS1.
7.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: BALB/c.
strain: C57BL/6J.
strain: NOD.
tissue: Bone marrow.
tissue: Head.
tissue: Heart.
tissue: Kidney.
tissue: Liver.
tissue: Lung.
tissue: Thymus.
8.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
9.

"Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1."
Kim Y.H. , Choi C.Y. , Kim Y.
Proc. Natl. Acad. Sci. U.S.A.96:12350-12355(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIPK1 AND HIPK2
10.

"The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice."
Nacerddine K. , Lehembre F. , Bhaumik M. , Artus J. , Cohen-Tannoudji M. , Babinet C. , Pandolfi P.P. , Dejean A.
Dev. Cell9:769-779(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
11.

"A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9."
Kashiwaba M. , Katsura K. , Ohnishi M. , Sasaki M. , Tanaka H. , Nishimune Y. , Kobayashi T. , Tamura S.
FEBS Lett.538:197-202(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPM1J
12.

"Interaction of moloney murine leukemia virus capsid with Ubc9 and PIASy mediates SUMO-1 addition required early in infection."
Yueh A. , Leung J. , Bhattacharyya S. , Perrone L.A. , de los Santos K. , Pu S.-Y. , Goff S.P.
J. Virol.80:342-352(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MOMLV CA
13.

"SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells."
Park S.W. , Hu X. , Gupta P. , Lin Y.P. , Ha S.G. , Wei L.N.
Nat. Struct. Mol. Biol.14:68-75(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NR2C1;FUNCTION IN NR2C1 SUMOYLATION
14.

"BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body."
Kuwata T. , Nakamura T.
Genes Cells13:931-940(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
15.

"The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G(1) arrest."
Bennett R.L. , Pan Y. , Christian J. , Hui T. , May W.S. Jr.
Cell Cycle11:407-417(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PRKRA AND TP53
16.

"Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system."
Tong H. , Hateboer G. , Perrakis A. , Bernards R. , Sixma T.K.
J. Biol. Chem.272:21381-21387(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS)

Product Feedback Wall

* Email:
*Comments: